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MMP inhibitors, such as batimastat, have been developed to bind competitively to the zinc active sites, inhibiting the abnormal regulation of MMPs and thus potentially preventing metastasis (European Cooperation in Science and Technology, 2012)

Due to their high reactivity, ROS typically oxidize targets with or adjacent to the intracellular compartment where they are produced, affecting surrounding neighboring cells

2.13.1.5 V717I (London mutation) Position 717 in the amyloid precursor protein (APP) is a well-established hotspot for mutations linked to autosomal dominant Alzheimers disease (ADAD)

Metabolic-epigenetic rewiring in CD8(+) T cells via lactate-dependent histone lactylation